表示可能な構造データがありません
C1C(NCS1)C(=O)N製品情報
1,3-thiazolidine-4-carboxamide (CAS 103749-87-7) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
想定用途
専門的研究・工業用途限定
データベース ID 9964101
安全上の注意
For professional research and industrial use only. Review the supplier safety data sheet before handling.
合成データ
12 反応 · 12 文献
反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-eb81ec449e0a40afbb36e255edf11c06反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-07b121c64e5847ddb030a5ba9c79e208反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-b38bded8771b4cdcb77f95a97a5da13b反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with and 4-thiazolidinecarboxamide (CAN 103749-87-7) in the presence of TBTU and DIEA to obtain the title compound as white solid; MS (EI): m/e=399.5 [MH+].
ソース ID: ord-40bd7372dfd94feb8b5d259ea4fc9ebb反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with and 4-thiazolidinecarboxamide (CAN 103749-87-7) in the presence of TBTU and DIEA to obtain the title compound as white solid; MS (EI): m/e=399.5 [MH+].
ソース ID: ord-40bd7372dfd94feb8b5d259ea4fc9ebb反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with and 4-thiazolidinecarboxamide (CAN 103749-87-7) in the presence of TBTU and DIEA. The mixture of enantiomers was separated by chiral HPLC (Reprosil Chiral NR). The (−) enantiomer was isolated as white solid; MS (EI): m/e=399.4 [MH+]; αD20 (DMSO)=−547.6°. The mixture of enantiomers was separated by chiral HPLC (Reprosil Chiral NR) The (−) enantiomer was isolated as white solid
ソース ID: ord-0ac6b95bcb5641d3a4f1b1fd101c73b1反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with and 4-thiazolidinecarboxamide (CAN 103749-87-7) in the presence of TBTU and DIEA. The mixture of enantiomers was separated by chiral HPLC (Reprosil Chiral NR). The (−) enantiomer was isolated as white solid; MS (EI): m/e=399.4 [MH+]; αD20 (DMSO)=−547.6°. The mixture of enantiomers was separated by chiral HPLC (Reprosil Chiral NR) The (−) enantiomer was isolated as white solid
ソース ID: ord-0ac6b95bcb5641d3a4f1b1fd101c73b1反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: The title compound was synthesized in analogy to Example 47 b, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 3 c, 100 mg, 429 μmol) and 4-thiazolidinecarboxamide (CAN 103749-87-7, 62.3 mg, 472 μmol) as starting materials and isolated (114 mg, 77%) as white solid; LC-MS (UV peak area, ESI) 100%, 348.1377 [MH+]. isolated (114 mg, 77%) as white solid
ソース ID: ord-b6df4d90c15b4b1b85de68a7779c03d5反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: The title compound was synthesized in analogy to Example 47 b, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 3 c, 100 mg, 429 μmol) and 4-thiazolidinecarboxamide (CAN 103749-87-7, 62.3 mg, 472 μmol) as starting materials and isolated (114 mg, 77%) as white solid; LC-MS (UV peak area, ESI) 100%, 348.1377 [MH+]. isolated (114 mg, 77%) as white solid
ソース ID: ord-b6df4d90c15b4b1b85de68a7779c03d5反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-eb81ec449e0a40afbb36e255edf11c06反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-07b121c64e5847ddb030a5ba9c79e208反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-b38bded8771b4cdcb77f95a97a5da13bPubChem References
化合物の公開データベース記録に掲載された情報源です。
関連製品
12 related records
CAS 1132901-59-7
CAS 1190416-54-6
CAS 1104608-10-7
CAS 1105700-51-3
CAS 88530-33-0
CAS 88530-32-9
CAS 620947-37-7
CAS 1251923-36-0
CAS 1251923-95-1
CAS 1218601-47-8
CAS 1251924-22-7
CAS 1251923-01-9
見積依頼
仕様、数量、納入先、用途をご連絡ください。供給可否を確認します。