(4-chlorophenyl)-trimethylsilane

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 4-Methylamino-4'-trimethylsilylbenzhydrol was prepared by a Grignard reagent formulated from 0.2 mole of 4-trimethylsilylchlorobenzene and 0.2 mole of magnesium with 0.2 mole of N-methylaminobenzaldehyde. 0.4 mole of the thus obtained 4-methylamino-4'-trimethylsilylbenzhydrol was dissolved in pyridine, and to the resultant solution was added, dropwise over a period of 40 hours at room temperature, an oxidizing agent prepared by adding 125 ml of pyridine to a solution of 7.5 ml of water and 12.5 mole of chromic anhydride under agitation while being cooled with water. The reaction product was refined by chromatography using silica gel, to obtain 41 g of 4-methylamino-4'-trimethylsilyl benzophenone in a yield of 38%. an oxidizing agent prepared

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 4-Methylamino-4'-trimethylsilylbenzhydrol was prepared by a Grignard reagent formulated from 0.2 mole of 4-trimethylsilylchlorobenzene and 0.2 mole of magnesium with 0.2 mole of N-methylaminobenzaldehyde. 0.4 mole of the thus obtained 4-methylamino-4'-trimethylsilylbenzhydrol was dissolved in pyridine, and to the resultant solution was added, dropwise over a period of 40 hours at room temperature, an oxidizing agent prepared by adding 125 ml of pyridine to a solution of 7.5 ml of water and 12.5 mole of chromic anhydride under agitation while being cooled with water. The reaction product was refined by chromatography using silica gel, to obtain 41 g of 4-methylamino-4'-trimethylsilyl benzophenone in a yield of 38%. an oxidizing agent prepared

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Various benzophenone derivatives were prepared in accordance with the same procedure as in Example 1 excepting that 0.2 mole of a benzaldehyde derivative was used instead of 4-dimethylaminobenzaldehyde and 0.2 mole of a halobenzene derivative was used instead of 4-trimethylsilylchlorobenzene. The particulars are set out as follows.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 4-Dimethylamino-4'-trimethylsilylbenzhydrol prepared from 4-dimethylaminobenzaldehyde and 4-trimethylsilylchlorobenzene was oxidized by a Cornforth reagent, to yield 4-dimethylamino-4'-trimethylsilyl benzophenone.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 4-Dimethylamino-4'-trimethylsilylbenzhydrol prepared from 4-dimethylaminobenzaldehyde and 4-trimethylsilylchlorobenzene was oxidized by a Cornforth reagent, to yield 4-dimethylamino-4'-trimethylsilyl benzophenone.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A Grignard reagent prepared from 0.2 mole of 4-trimethylsilylchlorobenzene and 0.2 mole of magnesium was reacted with 0.2 mole of 4-dimethylaminobenzaldehyde. The resulting reactant was subjected to oxidation by the Oppenauer method, to yield 4-dimethylamino-4'-trimethylsilyl benzophenone.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: C-1) A Gringnard reagent consisting of 0.2 mol of 4-trimethylsilylchlorobenzene and 0.2 mol of magnesium was prepared in tetrahydrofuran, mixed with 0.2 mol of 4-methylbenzaldehyde and subjected to Oppenauer oxidation reaction to obtain 4-methyl-4'-trimethylsilylbenzophenone represented by the following chemical structural formula: ##STR19## The reaction product was actually used in the form of a 15% solution in isopropyl alcohol. subjected to Oppenauer oxidation reaction

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: C-1) A Gringnard reagent consisting of 0.2 mol of 4-trimethylsilylchlorobenzene and 0.2 mol of magnesium was prepared in tetrahydrofuran, mixed with 0.2 mol of 4-methylbenzaldehyde and subjected to Oppenauer oxidation reaction to obtain 4-methyl-4'-trimethylsilylbenzophenone represented by the following chemical structural formula: ##STR19## The reaction product was actually used in the form of a 15% solution in isopropyl alcohol. subjected to Oppenauer oxidation reaction