tert-butyl N-[[(2R)-pyrrolidin-2-yl]methyl]carbamate;hydrochloride

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared as a solid according to the method of Example 81 using the product of Example 75 step i) and (R)-1-pyrrolidine-2-ylmethyl-carbamic acid tert-butyl ester hydrochloride. The product was purified using SCX ion-exchange chromatography (eluting with methanol followed by 3N ammonia in methanol), followed by HPLC. The product was purified SCX ion-exchange chromatography (eluting with methanol followed by 3N ammonia in methanol)

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared as a solid according to the method of Example 81 using the product of Example 75 step i) and (R)-1-pyrrolidine-2-ylmethyl-carbamic acid tert-butyl ester hydrochloride. The product was purified using SCX ion-exchange chromatography (eluting with methanol followed by 3N ammonia in methanol), followed by HPLC. The product was purified SCX ion-exchange chromatography (eluting with methanol followed by 3N ammonia in methanol)

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared as a solid according to the method of Example 81 using the product of Example 75 step i) and (R)-1-pyrrolidine-2-ylmethyl-carbamic acid tert-butyl ester hydrochloride. The product was purified using SCX ion-exchange chromatography (eluting with methanol followed by 3N ammonia in methanol), followed by HPLC. The product was purified SCX ion-exchange chromatography (eluting with methanol followed by 3N ammonia in methanol)