tert-butyl (3S)-piperidine-3-carboxylate

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: In a flask, dichloromethane (0.432 mL) was added to (S)-tert-butyl piperidine-3-carboxylate (0.020 g, 0.108 mmol). At 0° C., (1-bromoethyl)benzene (0.030 g, 0.162 mmol) was added to the reaction. The solution was allowed to stir from 0° C. to room temperature for 3 hrs. The reaction was quenched using water (1 mL) and extracted using dichloromethane (3×1 mL). The extractions were combined and dried using sodium sulfate. The extracts were concentrated in vacuo, and the crude product was progressed to the next step without further purification. The reaction was quenched extracted The extractions dried The extracts were concentrated in vacuo the crude product was progressed to the next step without further purification