(R)-1-(2,4-Dichlorophenyl)ethanamine

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 1.85 g of 1-(2,4-dichlorophenyl)ethylamine, 1.63 g of trimethyl orthopropionate and 0.46 g of Cyanamide were heated under reflux for about 30 minutes. The volatile components were removed under reduced pressure and the residue was then titrated with water. Filtration and drying gave 2.22 g of N′-cyano-N-[1-(2,4-dichlorophenyl)ethyl]propaneimidamide of logP of 2.56. under reflux for about 30 minutes The volatile components were removed under reduced pressure Filtration drying

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 1.85 g of 1-(2,4-dichlorophenyl)ethylamine, 1.63 g of trimethyl orthopropionate and 0.46 g of Cyanamide were heated under reflux for about 30 minutes. The volatile components were removed under reduced pressure and the residue was then titrated with water. Filtration and drying gave 2.22 g of N′-cyano-N-[1-(2,4-dichlorophenyl)ethyl]propaneimidamide of logP of 2.56. under reflux for about 30 minutes The volatile components were removed under reduced pressure Filtration drying