bis(4-chlorophenyl)methanamine

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from 2-chlorobenzimidazole and 4,4′-dichlorobenzhydrylamine (prepared by Procedure B from 4,4′-dichlorobenzophenone) by Procedure A. The product was isolated by preparative LCMS to give the title compound as the free base (white solid, mp 176-180° C.). MS(ES+) m/z 368 ([M+1]+, 100). 1NMR (DMSO-d6) δ6.19 (d, 1H), 6.82-6.90 (m, 2H), 7.10-7.16 (m, 2H), 7.40 (s, 8H), 7.69 (d, 1H), 10.6 (s, 1H). The product was isolated by preparative LCMS

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from 2-chlorobenzimidazole and 4,4′-dichlorobenzhydrylamine (prepared by Procedure B from 4,4′-dichlorobenzophenone) by Procedure A. The product was isolated by preparative LCMS to give the title compound as the free base (white solid, mp 176-180° C.). MS(ES+) m/z 368 ([M+1]+, 100). 1NMR (DMSO-d6) δ6.19 (d, 1H), 6.82-6.90 (m, 2H), 7.10-7.16 (m, 2H), 7.40 (s, 8H), 7.69 (d, 1H), 10.6 (s, 1H). The product was isolated by preparative LCMS

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Prepared in analogy to example 1.1 from C,C-bis-(4-chloro-phenyl)-methylamine (CA [14212-38-5]) and (3-phenyl-propionylamino)-acetic acid (CA [56613-60-6]).

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Prepared in analogy to example 1.1 from C,C-bis-(4-chloro-phenyl)-methylamine (CA [14212-38-5]) and (3-phenyl-propionylamino)-acetic acid (CA [56613-60-6]).

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from 2-chlorobenzimidazole and 4,4′-dichlorobenzhydrylamine (prepared by Procedure B from 4,4′-dichlorobenzophenone) by Procedure A. The product was isolated by preparative LCMS to give the title compound as the free base (white solid, mp 176-180° C.). MS(ES+) m/z 368 ([M+1]+, 100). 1NMR (DMSO-d6) δ6.19 (d, 1H), 6.82-6.90 (m, 2H), 7.10-7.16 (m, 2H), 7.40 (s, 8H), 7.69 (d, 1H), 10.6 (s, 1H). The product was isolated by preparative LCMS