2-(2,3-dihydro-1H-inden-2-yl)ethanamine

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 8.77 g (0.23 mol) of lithium aluminum hydride was suspended in 400 ml of tetrahydrofuran, to which was added a suspension of 100 ml tetrahydrofuran containing 27.8 g (0.160 mol) of (indan-2-yl)acetamide under ice-cooling. The mixture was stirred for 30 minutes at room temperature, then refluxed for 5 hours. Under ice-cooling, 9 ml of water, 9 ml of 15% sodium hydroxide and 26 ml water were added thereto dropwise in this order for decomposing the excessive reagent and separating the solid matter. The filtrate was condensed to obtain 26.1 g of an oily material. Yield: 100% was added cooling refluxed for 5 hours Under ice-cooling separating the solid matter condensed

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Suspended in 400 ml of tetrahydrofuran were 8.77 g (0.23 mol) of lithium aluminum hydride, and a suspension of 27.8 g (0.160 mol) of (indan-2-yl)acetamide in 100 ml of tetrahydro-furan was added under chilling with ice water. After stirring for 30 minutes at room temperature, the suspension mixture was refluxed for 5 hours. While chilling with ice water, 9 ml of water, 9 ml of 15% sodium hydroxide and 26 ml of water were added dropwise in that order to decompose excess of the reagents. Solids were separated by filtration, and the filtrate was concentrated, thereby obtaining 26.1 g of an oily substance. Yield: 100%. was added the suspension mixture was refluxed for 5 hours were added dropwise in that order Solids were separated by filtration the filtrate was concentrated obtaining 26.1 g of an oily substance