表示可能な構造データがありません
C1COCCN1C(C#N)C2=CC=CC=C2製品情報
2-morpholin-4-yl-2-phenylacetonitrile (CAS 15190-10-0) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
想定用途
専門的研究・工業用途限定
データベース ID 85812
安全上の注意
For professional research and industrial use only. Review the supplier safety data sheet before handling.
合成データ
8 反応 · 8 文献
反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-4c90a3462a0d409abd8fcb694e112f1f反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: NaH (0.975 mol) was washed with hexane. After the hexane was decanted off, the NaH was stirred in DMF (1950 mL) at room temperature. Morpholin-4-yl-phenyl-acetonitrile (0.70 mol) in DMF (300 mL) was added dropwise under N2 gas. The reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was cooled in an ice bath and 4-chloro-2-dimethoxymethyl-1-nitrobenzene (0.86 mol) in DMF (150 mL) was added dropwise. The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight. The reaction mixture was poured on ice/water and extracted with diisopropyl ether. The organic layer washed with water, dried (MgSO4) and evaporated to yield the title compound as a solid. After the hexane was decanted off The reaction mixture was stirred at room temperature for 2 hours The reaction mixture was cooled in an ice bath The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight The reaction mixture was poured on ice/water extracted with diisopropyl ether The organic layer washed with water dried (MgSO4) evaporated
ソース ID: ord-1d31b37ec4e2482dbbf6c21164ab279f反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: NaH (0.975 mol) was washed with hexane. After the hexane was decanted off, the NaH was stirred in DMF (1950 mL) at room temperature. Morpholin-4-yl-phenyl-acetonitrile (0.70 mol) in DMF (300 mL) was added dropwise under N2 gas. The reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was cooled in an ice bath and 4-chloro-2-dimethoxymethyl-1-nitrobenzene (0.86 mol) in DMF (150 mL) was added dropwise. The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight. The reaction mixture was poured on ice/water and extracted with diisopropyl ether. The organic layer washed with water, dried (MgSO4) and evaporated to yield the title compound as a solid. After the hexane was decanted off The reaction mixture was stirred at room temperature for 2 hours The reaction mixture was cooled in an ice bath The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight The reaction mixture was poured on ice/water extracted with diisopropyl ether The organic layer washed with water dried (MgSO4) evaporated
ソース ID: ord-1d31b37ec4e2482dbbf6c21164ab279f反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: NaH (0.975 mol) was washed with hexane. After the hexane was decanted off, the NaH was stirred in DMF (1950 mL) at room temperature. Morpholin-4-yl-phenyl-acetonitrile (0.70 mol) in DMF (300 mL) was added dropwise under N2 gas. The reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was cooled in an ice bath and 4-chloro-2-dimethoxymethyl-1-nitrobenzene (0.86 mol) in DMF (150 mL) was added dropwise. The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight. The reaction mixture was poured on ice/water and extracted with diisopropyl ether. The organic layer washed with water, dried (MgSO4) and evaporated to yield the title compound as a solid. After the hexane was decanted off The reaction mixture was stirred at room temperature for 2 hours The reaction mixture was cooled in an ice bath The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight The reaction mixture was poured on ice/water extracted with diisopropyl ether The organic layer washed with water dried (MgSO4) evaporated
ソース ID: ord-1d31b37ec4e2482dbbf6c21164ab279f反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-4c90a3462a0d409abd8fcb694e112f1f反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: NaH (0.975 mol) was washed with hexane. After the hexane was decanted off, the NaH was stirred in DMF (1950 mL) at room temperature. Morpholin-4-yl-phenyl-acetonitrile (0.70 mol) in DMF (300 mL) was added dropwise under N2 gas. The reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was cooled in an ice bath and 4-chloro-2-dimethoxymethyl-1-nitrobenzene (0.86 mol) in DMF (150 mL) was added dropwise. The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight. The reaction mixture was poured on ice/water and extracted with diisopropyl ether. The organic layer washed with water, dried (MgSO4) and evaporated to yield the title compound as a solid. After the hexane was decanted off The reaction mixture was stirred at room temperature for 2 hours The reaction mixture was cooled in an ice bath The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight The reaction mixture was poured on ice/water extracted with diisopropyl ether The organic layer washed with water dried (MgSO4) evaporated
ソース ID: ord-55a1f5e107c14e8697880f43e929cea7反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: NaH (0.975 mol) was washed with hexane. After the hexane was decanted off, the NaH was stirred in DMF (1950 mL) at room temperature. Morpholin-4-yl-phenyl-acetonitrile (0.70 mol) in DMF (300 mL) was added dropwise under N2 gas. The reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was cooled in an ice bath and 4-chloro-2-dimethoxymethyl-1-nitrobenzene (0.86 mol) in DMF (150 mL) was added dropwise. The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight. The reaction mixture was poured on ice/water and extracted with diisopropyl ether. The organic layer washed with water, dried (MgSO4) and evaporated to yield the title compound as a solid. After the hexane was decanted off The reaction mixture was stirred at room temperature for 2 hours The reaction mixture was cooled in an ice bath The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight The reaction mixture was poured on ice/water extracted with diisopropyl ether The organic layer washed with water dried (MgSO4) evaporated
ソース ID: ord-1106e43de9964d15ba9fc24340713797反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: NaH (0.975 mol) was washed with hexane. After the hexane was decanted off, the NaH was stirred in DMF (1950 mL) at room temperature. Morpholin-4-yl-phenyl-acetonitrile (0.70 mol) in DMF (300 mL) was added dropwise under N2 gas. The reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was cooled in an ice bath and 4-chloro-2-dimethoxymethyl-1-nitrobenzene (0.86 mol) in DMF (150 mL) was added dropwise. The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight. The reaction mixture was poured on ice/water and extracted with diisopropyl ether. The organic layer washed with water, dried (MgSO4) and evaporated to yield the title compound as a solid. After the hexane was decanted off The reaction mixture was stirred at room temperature for 2 hours The reaction mixture was cooled in an ice bath The reaction mixture was stirred at 0° C. for 2 hours and at room temperature overnight The reaction mixture was poured on ice/water extracted with diisopropyl ether The organic layer washed with water dried (MgSO4) evaporated
ソース ID: ord-1d31b37ec4e2482dbbf6c21164ab279fPubChem References
化合物の公開データベース記録に掲載された情報源です。
見積依頼
仕様、数量、納入先、用途をご連絡ください。供給可否を確認します。