5-chloro-2,2-diphenylpentanenitrile

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Using an equivalent quantity of 2,2-diphenyl-5-chlorovaleronitrile in place of the 2,2-diphenyl-4-bromobutyronitrile, and 3-azabicyclo[3.2.2]nonane in place of the piperidine used in Example 22, and substantially repeating the procedure detailed therein, affords 2,2-diphenyl-5-(3-azabicyclo[3.2.2]non-3-yl)valeronitrile hydrochloride, melting at about 272° - 273° C. This compound is represented by the following structural formula. ##STR17##

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Substitution of an equivalent quantity of 2,2-diphenyl-5-chlorovaleronitrile for the 2,2-diphenyl-4-bromobutyronitrile, and 1,4-diazabicyclo[4.4.0]decane for the piperidine used in Example 22, and substantial repetition of the procedure detailed therein, affords 2,2-diphenyl-5-(1,4-diazabicyclo[4.4.0]dec-4-yl)valeronitrile dihydrochloride, melting at about 233° - 238° C. with decomposition.