表示可能な構造データがありません
CN1CC2=CC=CC=C2CC1CO製品情報
(2-methyl-3,4-dihydro-1H-isoquinolin-3-yl)methanol (CAS 16880-87-8) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
想定用途
専門的研究・工業用途限定
データベース ID 589740
安全上の注意
For professional research and industrial use only. Review the supplier safety data sheet before handling.
合成データ
9 反応 · 9 文献
反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-9b38ae1f80f441de83dac0f158145263反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In 12 ml of acetone was dissolved 887 mg of 2-methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol, and 932 mg of methyl p-toluenesulfonate was added dropwise to the resulting solution. The mixture was stirred at room temperature for 3 hours to precipitate crystals. The crystals were collected by filtration, washed with acetone and dried under reduced pressure to give 1.31 g of the desired compound. was added dropwise to the resulting solution to precipitate crystals The crystals were collected by filtration washed with acetone dried under reduced pressure
ソース ID: ord-dd7d94056c554f6c9ba57702b4941e96反応条件: temp:140.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In a sealed tube, a mixture of 1.80 g of 1,2,3,4-tetrahydro-3-isoquinolinemethanol, 1.69 g of 90% formic acid and 1.04 g of 35% formalin was heated at 140° C. for 16 hours. The reaction solution was cooled and then made alkaline by addition of 10% aqueous sodium solution. Subsequently, potassium carbonate was added to the solution and a precipitated oil was extracted with chloroform. The extract was dried over anhydrous sodium sulfate and placed under reduced pressure to remove the solvent. There was obtained 1.95 g of 2-methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol. The reaction solution was cooled a precipitated oil was extracted with chloroform The extract was dried over anhydrous sodium sulfate to remove the solvent
ソース ID: ord-9ec459cf7bb44b60ac36b8358859f6a0反応条件: temp:140.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In a sealed tube, a mixture of 1.80 g of 1,2,3,4-tetrahydro-3-isoquinolinemethanol, 1.69 g of 90% formic acid and 1.04 g of 35% formalin was heated at 140° C. for 16 hours. The reaction solution was cooled and then made alkaline by addition of 10% aqueous sodium solution. Subsequently, potassium carbonate was added to the solution and a precipitated oil was extracted with chloroform. The extract was dried over anhydrous sodium sulfate and placed under reduced pressure to remove the solvent. There was obtained 1.95 g of 2-methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol. The reaction solution was cooled a precipitated oil was extracted with chloroform The extract was dried over anhydrous sodium sulfate to remove the solvent
ソース ID: ord-9ec459cf7bb44b60ac36b8358859f6a0反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-9b38ae1f80f441de83dac0f158145263反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In 12 ml of acetone was dissolved 887 mg of 2-methyl -1,2,3,4-tetrahydro-3-isoquinolinemethanol, and 932 mg of methyl p-toluenesulfonate was added dropwise to the resulting solution. The mixture was stirred at room temperature for 3 hours to precipitate crystals. The crystals were collected by filtration, washed with acetone and dried under reduced pressure to give 1.31 g of the desired compound. was added dropwise to the resulting solution to precipitate crystals The crystals were collected by filtration washed with acetone dried under reduced pressure
ソース ID: ord-da42e945887b41dbb884d6636e92d43c反応条件: temp:140.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In a sealed tube, a mixture of 1.80 g of 1,2,3,4-tetrahydro-3-isoquinolinemethanol, 1.69 g of 90% formic acid and 1.04 g of 35% formalin was heated at 140° C. for 16 hours. The reaction solution was cooled and then made alkaline by addition of 10% aqueous sodium solution. Subsequently, potassium carbonate was added to the solution and a precipitated oil was extracted with chloroform. The extract was dried over anhydrous sodium sulfate and placed under reduced pressure to remove the solvent. There was obtained 1.95 g of 2-methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol. The reaction solution was cooled a precipitated oil was extracted with chloroform The extract was dried over anhydrous sodium sulfate to remove the solvent
ソース ID: ord-5a05dda084ce464681427f416f392cdf反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In 12 ml of acetone was dissolved 887 mg of 2-methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol, and 932 mg of methyl p-toluenesulfonate was added dropwise to the resulting solution. The mixture was stirred at room temperature for 3 hours to precipitate crystals. The crystals were collected by filtration, washed with acetone and dried under reduced pressure to give 1.31 g of the desired compound. was added dropwise to the resulting solution to precipitate crystals The crystals were collected by filtration washed with acetone dried under reduced pressure
ソース ID: ord-dd7d94056c554f6c9ba57702b4941e96反応条件: temp:140.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: In a sealed tube, a mixture of 1.80 g of 1,2,3,4-tetrahydro-3-isoquinolinemethanol, 1.69 g of 90% formic acid and 1.04 g of 35% formalin was heated at 140° C. for 16 hours. The reaction solution was cooled and then made alkaline by addition of 10% aqueous sodium solution. Subsequently, potassium carbonate was added to the solution and a precipitated oil was extracted with chloroform. The extract was dried over anhydrous sodium sulfate and placed under reduced pressure to remove the solvent. There was obtained 1.95 g of 2-methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol. The reaction solution was cooled a precipitated oil was extracted with chloroform The extract was dried over anhydrous sodium sulfate to remove the solvent
ソース ID: ord-9ec459cf7bb44b60ac36b8358859f6a0PubChem References
化合物の公開データベース記録に掲載された情報源です。
見積依頼
仕様、数量、納入先、用途をご連絡ください。供給可否を確認します。