(2S,3S,4S,5R)-2-methoxyoxane-3,4,5-triol

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A known compound, methyl α-D-lyxopyranoside [Compound (1)] of the formula ##STR8## is reacted with diethylaminosulfur trifluoride [(C2H5)2 NSF3 ] to fluorinate selectively only the 4-hydroxyl group of Compound (1), whereby there is produced methyl 4-deoxy-4-fluoro-α-L-ribopyranoside [Compound (2)] of the formula ##STR9## as a 4-deoxy-4-fluoro derivative of Compound (1), with accompanying reversion of the steric configuration of the starting compound.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A known compound, methyl α-D-lyxopyranoside [Compound 50] of the formula ##STR90## is reacted with diethylaminosulfur trifluoride [(C2H5)2 NSF3 ] to fluorinate selectively only the 4-hydroxyl group of Compound 50, whereby there is produced methyl 4-deoxy-4-fluoro-α-L-ribopyranoside [Compound 51] of the formula ##STR91## as a 4-deoxy-4-fluoro derivative of Compound 50, with accompanying reversion of the steric configuration of the starting compound.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A known compound, methyl α-D-lyxopyranoside [Compound 50] of the formula ##STR90## is reacted with diethylaminosulfur trifluoride [(C2H5)2 NSF3 ] to fluorinate selectively only the 4-hydroxyl group of Compound 50, whereby there is produced methyl 4-deoxy-4-fluoro-α-L-ribopyranoside [Compound 51] of the formula ##STR91## as a 4-deoxy-4-fluoro derivative of Compound 50, with accompanying reversion of the steric configuration of the starting compound.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A known compound, methyl α-D-lyxopyranoside [Compound (1)] of the formula ##STR9## is reacted with diethylaminosulfur trifluoride [(C2H5)2 NSF3 ] to fluorinate selectively only the 4-hydroxyl group of Compound (1), whereby there is produced methyl 4-deoxy-4-fluoro-α-L-ribopyranoside [Compound (2)] of the formula ##STR10## as a 4-deoxy-4-fluoro derivative of Compound (1), with accompanying reversion of the steric configuration of the starting compound.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A known compound, methyl α-D-lyxopyranoside [Compound (1)] of the formula ##STR9## is reacted with diethylaminosulfur trifluoride [(C2H5)2 NSF3 ] to fluorinate selectively only the 4-hydroxyl group of Compound (1), whereby there is produced methyl 4-deoxy-4-fluoro-α-L-ribopyranoside [Compound (2)] of the formula ##STR10## as a 4-deoxy-4-fluoro derivative of Compound (1), with accompanying reversion of the steric configuration of the starting compound.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A known compound, methyl α-D-lyxopyranoside [Compound (1)] of the formula ##STR8## is reacted with diethylaminosulfur trifluoride [(C2H5)2 NSF3 ] to fluorinate selectively only the 4-hydroxyl group of Compound (1), whereby there is produced methyl 4-deoxy-4-fluoro-α-L-ribopyranoside [Compound (2)] of the formula ##STR9## as a 4-deoxy-4-fluoro derivative of Compound (1), with accompanying reversion of the steric configuration of the starting compound.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A known compound, methyl α-D-lyxopyranoside [Compound 50] of the formula ##STR90## is reacted with diethylaminosulfur trifluoride [(C2H5)2 NSF3 ] to fluorinate selectively only the 4-hydroxyl group of Compound 50, whereby there is produced methyl 4-deoxy-4-fluoro-α-L-ribopyranoside [Compound 51] of the formula ##STR91## as a 4-deoxy-4-fluoro derivative of Compound 50, with accompanying reversion of the steric configuration of the starting compound.