2,3-dichloropropanamide

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is prepared by reacting sodium 3acetamido-5-chlorobenzenesulfinate in aqueous ethanol solution, in the presence of potassium acetate, with 2,3-dichloropropionamide. The resulting 2-carboxyamidovinyl 3-acetamido-5-chlorophenyl sulfone is hydrolyzed with dilute hydrochloric acid to give 2carboxyamidovinyl 3-amino-5-chlorophenyl sulfone. The dried solid is boiled with ethanol under reflux for 2 hours in the presence of concentrated sulfuric acid. After drowning in water and neutralization 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is obtained.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is prepared by reacting sodium 3acetamido-5-chlorobenzenesulfinate in aqueous ethanol solution, in the presence of potassium acetate, with 2,3-dichloropropionamide. The resulting 2-carboxyamidovinyl 3-acetamido-5-chlorophenyl sulfone is hydrolyzed with dilute hydrochloric acid to give 2carboxyamidovinyl 3-amino-5-chlorophenyl sulfone. The dried solid is boiled with ethanol under reflux for 2 hours in the presence of concentrated sulfuric acid. After drowning in water and neutralization 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is obtained.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is prepared by reacting sodium 3acetamido-5-chlorobenzenesulfinate in aqueous ethanol solution, in the presence of potassium acetate, with 2,3-dichloropropionamide. The resulting 2-carboxyamidovinyl 3-acetamido-5-chlorophenyl sulfone is hydrolyzed with dilute hydrochloric acid to give 2carboxyamidovinyl 3-amino-5-chlorophenyl sulfone. The dried solid is boiled with ethanol under reflux for 2 hours in the presence of concentrated sulfuric acid. After drowning in water and neutralization 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is obtained.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is prepared by reacting sodium 3acetamido-5-chlorobenzenesulfinate in aqueous ethanol solution, in the presence of potassium acetate, with 2,3-dichloropropionamide. The resulting 2-carboxyamidovinyl 3-acetamido-5-chlorophenyl sulfone is hydrolyzed with dilute hydrochloric acid to give 2carboxyamidovinyl 3-amino-5-chlorophenyl sulfone. The dried solid is boiled with ethanol under reflux for 2 hours in the presence of concentrated sulfuric acid. After drowning in water and neutralization 2-carbethoxyvinyl 3-amino-5-chlorophenyl sulfone is obtained.