3-dimethoxyphosphoryl-N-(hydroxymethyl)propanamide

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A 10 g of PA was dissolved into a 200 cm3 of chloroform and a 12.8 g of MDPA was slowly added thereto. Then, the solution was stirred for 2 hours at room temperature. After the completion of the reaction in the solution, the raw materials were removed by means of a silica gel column to obtain a 500 cm3 of PA-MDPA/chloroform solution. The solution was then condensed to 100 cm3 and washed with a 50 cm3 of water for three times. Then, it was dried with magnesium sulfate and, after drying, the chloroform was removed to produce a 16.4 g of PA-MDPA. After the completion of the reaction in the solution the raw materials were removed by means of a silica gel column