propyl N-[3-(dimethylamino)propyl]carbamate

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 14.1 g (0.075 mole) of N-(dimethylaminopropyl)-carbamic acid propylester are dissolved in 200 ml of ether. While stirring, 9.15 g (0.075 mole) of benzoic acid in 30 ml of tetrahydrofurane are added in drops. Agitation is continued for 2 hours, the solvent is distilled, and the oil dried in vacuum. One obtains 23.1 g (99.4% of the theory) of nD20 = 1.5070. the solvent is distilled the oil dried in vacuum One obtains 23.1 g (99.4% of the theory) of nD20 = 1.5070

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 11.0 g (0.0585 mole) of N-(3-dimethylaminopropyl)-carbamic acid propylester are dissolved in 200 ml of ether. While stirring and cooling, 3.2 ml (0.06 mole) of concentrated sulfuric acid are added in drops. Agitation is continued for 2 hours at room temperature, the ether is decanted, the oil is washed with ether and dried in vacuum. One obtains 15.0 g (89.7% of the theory) of the Mp. 44°-50° C. cooling the ether is decanted the oil is washed with ether dried in vacuum One obtains 15.0 g (89.7% of the theory) of the Mp. 44°-50° C.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 11.0 g (0.0585 mole) of N-(3-dimethylaminopropyl)-carbamic acid propylester are dissolved in 200 ml of ether. While stirring and cooling, 3.2 ml (0.06 mole) of concentrated sulfuric acid are added in drops. Agitation is continued for 2 hours at room temperature, the ether is decanted, the oil is washed with ether and dried in vacuum. One obtains 15.0 g (89.7% of the theory) of the Mp. 44°-50° C. cooling the ether is decanted the oil is washed with ether dried in vacuum One obtains 15.0 g (89.7% of the theory) of the Mp. 44°-50° C.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 11.0 g (0.0585 mole) of N-(3-dimethylaminopropyl)-carbamic acid propylester are dissolved in 200 ml of ether. While stirring and cooling, 3.2 ml (0.06 mole) of concentrated sulfuric acid are added in drops. Agitation is continued for 2 hours at room temperature, the ether is decanted, the oil is washed with ether and dried in vacuum. One obtains 15.0 g (89.7% of the theory) of the Mp. 44°-50° C. cooling the ether is decanted the oil is washed with ether dried in vacuum One obtains 15.0 g (89.7% of the theory) of the Mp. 44°-50° C.