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CC1(CC(CC(C1)(C)C)O)C製品情報
3,3,5,5-tetramethylcyclohexan-1-ol (CAS 2650-40-0) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
想定用途
専門的研究・工業用途限定
データベース ID 75851
安全上の注意
For professional research and industrial use only. Review the supplier safety data sheet before handling.
合成データ
12 反応 · 12 文献
反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-f87ce83c91d045b1a4de907a924dcc2c反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-2fe37baea9ca477d8be71e7a0f382a79反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: 3,3,5,5-Tetramethylcyclohexanol (7.81 g, 0.05 mol), 4-hydroxyphenylacetic acid (7.6 g, 0.05 mol), p-toluenesulfonic acid (2 g) and benzene (200 mL) were refluxed with continuous water separation for 8 hours. The reaction mixture was evaporated, the oily residue was dissolved in ethyl acetate (100 mL), washed first with aqueous 5% NaHCO3 solution (100 mL) and then twice with water (200 mL ), then dried over anhydrous MgSO4. The solvent was evaporated under reduced pressure to give 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate as a solid (7.00 g, 82.0% yield). The reaction mixture was evaporated the oily residue was dissolved in ethyl acetate (100 mL) washed first with aqueous 5% NaHCO3 solution (100 mL) twice with water (200 mL ), then dried over anhydrous MgSO4 The solvent was evaporated under reduced pressure
ソース ID: ord-9376069414fb459199cd0b5b99e98ede反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: A mixture of 4-hydroxyphenylacetic acid (6.08 g), 3,3,5,5-tetramethylcyclohexyl alcohol (6.24 g), p-toluenesulfonic acid (1 g) and benzene (300 mL) was refluxed for 8 hours with continuous water separation. The mixture was cooled and washed with 10% Na2CO3, then with water. Drying over MgSO4 and evaporation in vacuo yielded 12.3 g of 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate. That product, which can be represented by the structural formula ##STR27## is characterized by the following NMR (CDCl3, TMS, ppm): 7.00(d, J=8 Hz, 2H), 6.60(d, J=8 Hz, 2H), 5.00(broad, 1H), 3.40(s, 2H) and 1.8-0.80(m, 18H). The mixture was cooled washed with 10% Na2CO3 Drying over MgSO4 and evaporation in vacuo
ソース ID: ord-664f91060a714a78a491690226a1bc18反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-f87ce83c91d045b1a4de907a924dcc2c反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: 3,3,5,5-Tetramethylcyclohexanol (7.81 g, 0.05 mol), 4-hydroxyphenylacetic acid (7.6 g, 0.05 mol), p-toluenesulfonic acid (2 g) and benzene (200 mL) were refluxed with continuous water separation for 8 hours. The reaction mixture was evaporated, the oily residue was dissolved in ethyl acetate (100 mL), washed first with aqueous 5% NaHCO3 solution (100 mL) and then twice with water (200 mL), then dried over anhydrous MgSO4. The solvent was evaporated under reduced pressure to give 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate as a solid (7.00 g, 82.0% yield). The reaction mixture was evaporated the oily residue was dissolved in ethyl acetate (100 mL) washed first with aqueous 5% NaHCO3 solution (100 mL) twice with water (200 mL), then dried over anhydrous MgSO4 The solvent was evaporated under reduced pressure
ソース ID: ord-37910b6ca01e4c0395ced3c8248ed015反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: 3,3,5,5-Tetramethylcyclohexanol (7.81 g, 0.05 mol), 4-hydroxyphenylacetic acid (7.6 g, 0.05 mol), p-toluenesulfonic acid (2 g) and benzene (200 mL) were refluxed with continuous water separation for 8 hours. The reaction mixture was evaporated, the oily residue was dissolved in ethyl acetate (100 mL), washed first with aqueous 5% NaHCO3 solution (100 mL) and then twice with water (200 mL), then dried over anhydrous MgSO4. The solvent was evaporated under reduced pressure to give 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate as a solid (7.00 g, 82.0% yield). The reaction mixture was evaporated the oily residue was dissolved in ethyl acetate (100 mL) washed first with aqueous 5% NaHCO3 solution (100 mL) twice with water (200 mL), then dried over anhydrous MgSO4 The solvent was evaporated under reduced pressure
ソース ID: ord-37910b6ca01e4c0395ced3c8248ed015反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: A mixture of 4-hydroxyphenylacetic acid (6.08 g), 3,3,5,5-tetramethylcyclohexyl alcohol (6.24 g), p-toluenesulfonic acid (1 g) and benzene (300 mL) was refluxed for 8 hours with continuous water separation. The mixture was cooled and washed with 10% Na2CO3, then with water. Drying over MgSO4 and evaporation in vacuo yielded 12.3 g of 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate. That product, which can be represented by the structural formula ##STR26## is characterized by the following NMR (CDCl3, TMS, ppm): 7.00 (d, J=8Hz, 2H), 6.60 (d, J=8Hz, 2H), 5.00 (broad, 1H), 3.40 (s, 2H) and 1.80-0.80 (m, 18H). The mixture was cooled washed with 10% Na2CO3 Drying over MgSO4 and evaporation in vacuo
ソース ID: ord-9913684e8ce944ceae38e91f1a629b9c反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: A mixture of 4-hydroxyphenylacetic acid (6.08 g), 3,3,5,5-tetramethylcyclohexyl alcohol (6.24 g), p-toluenesulfonic acid (1 g) and benzene (300 mL) was refluxed for 8 hours with continuous water separation. The mixture was cooled and washed with 10% Na2CO3, then with water. Drying over MgSO4 and evaporation in vacuo yielded 12.3 g of 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate. That product, which can be represented by the structural formula ##STR26## is characterized by the following NMR (CDCl3, TMS, ppm): 7.00 (d, J=8Hz, 2H), 6.60 (d, J=8Hz, 2H), 5.00 (broad, 1H), 3.40 (s, 2H) and 1.80-0.80 (m, 18H). The mixture was cooled washed with 10% Na2CO3 Drying over MgSO4 and evaporation in vacuo
ソース ID: ord-9913684e8ce944ceae38e91f1a629b9c反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: 3,3,5,5-Tetramethylcyclohexanol (7.81 g, 0.05 mol), 4-hydroxyphenylacetic acid (7.6 g, 0.05 mol), p-toluenesulfonic acid (2 g) and benzene (200 mL) were refluxed with continuous water separation for 8 hours. The reaction mixture was evaporated, the oily residue was dissolved in ethyl acetate (100 mL), washed first with aqueous 5% NaHCO3 solution (100 mL) and then twice with water (200 mL ), then dried over anhydrous MgSO4. The solvent was evaporated under reduced pressure to give 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate as a solid (7.00 g, 82.0% yield). The reaction mixture was evaporated the oily residue was dissolved in ethyl acetate (100 mL) washed first with aqueous 5% NaHCO3 solution (100 mL) twice with water (200 mL ), then dried over anhydrous MgSO4 The solvent was evaporated under reduced pressure
ソース ID: ord-9376069414fb459199cd0b5b99e98ede反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: A mixture of 4-hydroxyphenylacetic acid (6.08 g), 3,3,5,5-tetramethylcyclohexyl alcohol (6.24 g), p-toluenesulfonic acid (1 g) and benzene (300 mL) was refluxed for 8 hours with continuous water separation. The mixture was cooled and washed with 10% Na2CO3, then with water. Drying over MgSO4 and evaporation in vacuo yielded 12.3 g of 3,3,5,5-tetramethylcyclohexyl 4-hydroxyphenylacetate. That product, which can be represented by the structural formula ##STR27## is characterized by the following NMR (CDCl3, TMS, ppm): 7.00(d, J=8 Hz, 2H), 6.60(d, J=8 Hz, 2H), 5.00(broad, 1H), 3.40(s, 2H) and 1.8-0.80(m, 18H). The mixture was cooled washed with 10% Na2CO3 Drying over MgSO4 and evaporation in vacuo
ソース ID: ord-664f91060a714a78a491690226a1bc18反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-2fe37baea9ca477d8be71e7a0f382a79PubChem References
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