(1R,2S)-2-(aminomethyl)cyclohexan-1-ol;hydrochloride

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was synthesized in analogy to Example 102, using 5-bromo-6-hydroxy-nicotinic acid methyl ester, 2-methoxyethanol, (4-chloro-phenyl)-boronic acid and trans-2-aminomethyl-1-cyclohexanol hydrochloride as starting materials to yield racemic 5-(4-chloro-phenyl)-N-((1SR,2RS)-2-hydroxy-cyclohexylmethyl)-6-(2-methoxy-ethoxy)-nicotinamide. MS (ISP) 419.1 (M+H)+. The title compound was synthesized in analogy to Example 102