N,N-diphenylbenzamide

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 4'-[2-(1-Piperidyl)ethoxy]-N-phenylbenzanilide [IA; R is C6H5, Ar is -C6H4 -(p), Y is CH2CH2, N=Z is N(CH2)5, n is O, Ar' is C6H5 ] was prepared from 11.5 g. of 4'-hydroxy-N-phenylbenzanilide and 2-(1-piperidyl)ethyl chloride in the presence of sodium methoxide according to the procedure of Example 1. The product was recrystallized from benzene-hexane to give 4'-]2-(1-piperidyl)ethoxy]-N-phenylbenzanilide, colorless solid, m.p. 78.5°-82.5°C.; cyclohexanesulfamic acid salt form, m.p. 151.5°-157.5°C. was prepared from 11.5 g The product was recrystallized from benzene-hexane