2-methyl-6-(2,2,2-trifluoroethoxy)aniline

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To 60 ml of an ethanol solution containing 10 g (42.6 mmol) of 2-nitro-3-(2,2,2-trifluoroethoxy)toluene, 1 g of 5 wt% Pd-carbon catalyst, and catalytic reduction was performed at atmospheric pressure and room temperature. After performing thin-layer chromatography to confirm that all the starting material had been consumed, the catalyst was filtered off and the filtrate was concentrated to provide 8.7 g of 2-methyl-6-(2,2,2-trifluoroethoxy)aniline as an oil. was performed at atmospheric pressure and room temperature had been consumed the catalyst was filtered off the filtrate was concentrated

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To a mixture of 2-nitro-3-(2,2,2-trifluoroethyl)oxytoluene (4.12 g) and ethyl acetate (30 ml) was added a catalytic amount of 10% palladium/carbon. Then, the mixture was stirred under a hydrogen atmosphere for 4 hours. The catalyst was removed from the reaction solution by filtration, and the filtrate was concentration under reduced pressure to yield the title compound (3.71 g). The catalyst was removed from the reaction solution by filtration concentration under reduced pressure

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To 60 ml of an ethanol solution containing 10 g (42.6 mmol) of 2-nitro-3-(2,2,2-trifluoroethoxy)toluene, 1 g of 5 wt% Pd-carbon catalyst, and catalytic reduction was performed at atmospheric pressure and room temperature. After performing thin-layer chromatography to confirm that all the starting material had been consumed, the catalyst was filtered off and the filtrate was concentrated to provide 8.7 g of 2-methyl-6-(2,2,2-trifluoroethoxy)aniline as an oil. was performed at atmospheric pressure and room temperature had been consumed the catalyst was filtered off the filtrate was concentrated