1-N',3-N'-bis(benzenecarbonothioyl)-1-N',3-N'-dimethylpropanedihydrazide

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To a solution of N′1,N′3-dimethyl-N′1,N′3-di(phenylcarbonothioyl)malonohydrazide (a, 2.0 mmol) in TEA (5 mL) and DCM (10 mL) was added dropwise acetyl chloride (4.0 mmol) and the mixture was stirred at rt for 12 h before quenching with aqueous 1N NaHCO3 (10 mL). The organic layer was separated and evaporated. The residue was purified by flash chromatography to give b as yellow solids (7 mg). before quenching with aqueous 1N NaHCO3 (10 mL) The organic layer was separated evaporated The residue was purified by flash chromatography

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To a solution of N′1,N′3-dimethyl-N′1,N′3-di(phenylcarbonothioyl)malonohydrazide (a, 2.0 mmol) in TEA (5 mL) and DCM (10 mL) was added dropwise acetyl chloride (4.0 mmol) and the mixture was stirred at rt for 12 h before quenching with aqueous 1N NaHCO3 (10 mL). The organic layer was separated and evaporated. The residue was purified by flash chromatography to give b as yellow solids (7 mg). before quenching with aqueous 1N NaHCO3 (10 mL) The organic layer was separated evaporated The residue was purified by flash chromatography