表示可能な構造データがありません
C1=CC=C(C=C1)CNCC2=CC=CC=C2O製品情報
2-[(benzylamino)methyl]phenol (CAS 5001-26-3) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
想定用途
専門的研究・工業用途限定
データベース ID 408360
安全上の注意
For professional research and industrial use only. Review the supplier safety data sheet before handling.
合成データ
12 反応 · 12 文献
反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-2ab6ba81821b42c68b60f8df89d25c66反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-81df99d6b18941b3865db926b79d6976反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: This compound was prepared from 1.0 g of 2-(benzylimino-methyl)-4-methoxy-phenol and 0.18 g of sodium borohydride using the procedure described 64b. Yield: 1.0 g (oil), EI-MS: 243 (M+).
ソース ID: ord-263f1cab6e32486b9aaa8be01ab640e4反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: This compound was prepared from 1.0 g of 2-(benzylimino-methyl)-4-methoxy-phenol and 0.18 g of sodium borohydride using the procedure described 64b. Yield: 1.0 g (oil), EI-MS: 243 (M+).
ソース ID: ord-263f1cab6e32486b9aaa8be01ab640e4反応条件: temp:0.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: A mixture of 19.0 g of 2-(benzylamino-methyl)-phenol and 75 mL of toluene was cooled to 0° C., and a solution of chloroacetyl chloride (7.8 mL) in 75 mL of toluene was slowly added while stirring. Stirring was continued for 16 h. Dry N,N-dimethylformamide (60 mL) was added and the solution was cooled to 0° C. In a nitrogen atmosphere 3:4 g of sodium hydride (95%; dispersion in mineral oil) were added in small portions and the mixture was allowed to stir at room temperature for 2 h. Water was added and the aqueous layer was extracted with ethyl acetate. The combined organic extracts were dried (sodium sulfate) and the solvent was removed in vacuo yielding 12.4 g of 4-benzyl-4,5-dihydro-benzo[f][1,4]oxazepin-3-one. M.p. 95-97° C., Stirring the solution was cooled to 0° C to stir at room temperature for 2 h the aqueous layer was extracted with ethyl acetate The combined organic extracts were dried (sodium sulfate) the solvent was removed in vacuo
ソース ID: ord-ba653ed80763485393094f40da115fd9反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: Sodium borohydride (0.2 g) was added in small portions to 3 mL of dry 2-propanol in a nitrogen atmosphere. To this mixture was added dropwise a solution of 1.0 g of 2-(benzylimino-methyl)-phenol in 3 mL of 2-propanol. After complete addition, stirring was continued for 1 h. Then water was added in order to decompose excess borohydride, and the volatiles were removed in vacuo. The residue was redissolved in ethyl acetate, washed with water, dried (sodium sulfate) and concentrated yielding 0.9 g of 2-(benzylamino-methyl)-phenol as an oil. EI-MS: 213 (M+). After complete addition the volatiles were removed in vacuo The residue was redissolved in ethyl acetate washed with water dried (sodium sulfate) concentrated
ソース ID: ord-6c93f9cb25fe4e1da7bc99a37d5557d1反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: Sodium borohydride (0.2 g) was added in small portions to 3 mL of dry 2-propanol in a nitrogen atmosphere. To this mixture was added dropwise a solution of 1.0 g of 2-(benzylimino-methyl)-phenol in 3 mL of 2-propanol. After complete addition, stirring was continued for 1 h. Then water was added in order to decompose excess borohydride, and the volatiles were removed in vacuo. The residue was redissolved in ethyl acetate, washed with water, dried (sodium sulfate) and concentrated yielding 0.9 g of 2-(benzylamino-methyl)-phenol as an oil. EI-MS: 213 (M+). After complete addition the volatiles were removed in vacuo The residue was redissolved in ethyl acetate washed with water dried (sodium sulfate) concentrated
ソース ID: ord-6c93f9cb25fe4e1da7bc99a37d5557d1反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: This compound was prepared from 1.0 g of 2-(benzylimino-methyl)-4-methoxy-phenol and 0.18 g of sodium borohydride using the procedure described 64b. Yield: 1.0 g (oil), EI-MS: 243 (M+).
ソース ID: ord-03d9a866b8c9456385fc755b34bbbd49反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: This compound was prepared from 1.0 g of 2-(benzylimino-methyl)-4-methoxy-phenol and 0.18 g of sodium borohydride using the procedure described 64b. Yield: 1.0 g (oil), EI-MS: 243 (M+).
ソース ID: ord-03d9a866b8c9456385fc755b34bbbd49反応条件: temp:0.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: A mixture of 19.0 g of 2-(benzylamino-methyl)-phenol and 75 mL of toluene was cooled to 0° C., and a solution of chloroacetyl chloride (7.8 mL) in 75 mL of toluene was slowly added while stirring. Stirring was continued for 16 h. Dry N,N-dimethylformamide (60 mL) was added and the solution was cooled to 0° C. In a nitrogen atmosphere 3.4 g of sodium hydride (95%; dispersion in mineral oil) were added in small portions and the mixture was allowed to stir at room temperature for 2 h. Water was added and the aqueous layer was extracted with ethyl acetate. The combined organic extracts were dried (sodium sulfate) and the solvent was removed in vacuo yielding 12.4 g of 4-benzyl-4,5-dihydro-benzo[f][1,4]oxazepin-3-one. M.p. 95-97° C., EI-MS: 253 (M+). Stirring the solution was cooled to 0° C to stir at room temperature for 2 h the aqueous layer was extracted with ethyl acetate The combined organic extracts were dried (sodium sulfate) the solvent was removed in vacuo
ソース ID: ord-ac8be870fe954ec1be8fb77802f3ae67反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: Sodium borohydride (0.2 g) was added in small portions to 3 mL of dry 2-propanol in a nitrogen atmosphere. To this mixture was added dropwise a solution of 1.0 g of 2-(benzylimino-methyl)-phenol in 3 mL of 2-propanol. After complete addition, stirring was continued for 1 h. Then water was added in order to decompose excess borohydride, and the volatiles were removed in vacuo. The residue was redissolved in ethyl acetate, washed with water, dried (sodium sulfate) and concentrated yielding 0.9 g of 2-(benzylamino-methyl)-phenol as an oil. EI-MS: 213 (M+). After complete addition the volatiles were removed in vacuo The residue was redissolved in ethyl acetate washed with water dried (sodium sulfate) concentrated
ソース ID: ord-e5c58b6a217b48718b255c5b288ea419反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: Sodium borohydride (0.2 g) was added in small portions to 3 mL of dry 2-propanol in a nitrogen atmosphere. To this mixture was added dropwise a solution of 1.0 g of 2-(benzylimino-methyl)-phenol in 3 mL of 2-propanol. After complete addition, stirring was continued for 1 h. Then water was added in order to decompose excess borohydride, and the volatiles were removed in vacuo. The residue was redissolved in ethyl acetate, washed with water, dried (sodium sulfate) and concentrated yielding 0.9 g of 2-(benzylamino-methyl)-phenol as an oil. EI-MS: 213 (M+). After complete addition the volatiles were removed in vacuo The residue was redissolved in ethyl acetate washed with water dried (sodium sulfate) concentrated
ソース ID: ord-e5c58b6a217b48718b255c5b288ea419PubChem References
化合物の公開データベース記録に掲載された情報源です。