N',N'-diethylbut-2-yne-1,4-diamine

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A solution of 4-diethylamino-2-butynylamine (0.14 g) in benzene (2.5 ml) was added dropwise to a solution of 2-chloro-2-cyclohexyl-2-phenylacetyl chloride (0.27 g) in benzene (2.5 ml below 25° C. After being stirred at room temperature for 19.5 hours, the resulting precipitates were collected by filtration and recrystallized from a mixture of acetone and diethyl ether to give N-(4-diethylamino-2-butynyl)-2-chloro-2-cyclohexyl-2-phenylacetamide hydrochloride (0.19 g). the resulting precipitates were collected by filtration recrystallized from a mixture of acetone and diethyl ether

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A solution of 4-diethylamino-2-butynylamine (0.14 g) in benzene (2.5 ml) was added dropwise to a solution of 2-chloro-2-cyclohexyl-2-phenylacetyl chloride (0.27 g) in benzene (2.5 ml below 25° C. After being stirred at room temperature for 19.5 hours, the resulting precipitates were collected by filtration and recrystallized from a mixture of acetone and diethyl ether to give N-(4-diethylamino-2-butynyl)-2-chloro-2-cyclohexyl-2-phenylacetamide hydrochloride (0.19 g). the resulting precipitates were collected by filtration recrystallized from a mixture of acetone and diethyl ether

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A solution of 4-diethylamino-2-butynylamine (0.14 g) in benzene (2.5 ml) was added dropwise to a solution of 2-chloro-2-cyclohexyl-2-phenylacetyl chloride (0.27 g) in benzene (2.5 ml) below 25° C. After being stirred at room temperature for 19.5 hours, the resulting precipitates were collected by filtration and recrystallized from a mixture of acetone and diethyl ether to give N-(4-diethylamino-2-butynyl)-2-chloro-2-cyclohexyl-2-phenylacetamide hydrochloride (0.19 g). the resulting precipitates were collected by filtration recrystallized from a mixture of acetone and diethyl ether

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A solution of 4-diethylamino-2-butynylamine (0.14 g) in benzene (2.5 ml) was added dropwise to a solution of 2-chloro-2-cyclohexyl-2-phenylacetyl chloride (0.27 g) in benzene (2.5 ml below 25° C. After being stirred at room temperature for 19.5 hours, the resulting precipitates were collected by filtration and recrystallized from a mixture of acetone and diethyl ether to give N-(4-diethylamino-2-butynyl)-2-chloro-2-cyclohexyl-2-phenylacetamide hydrochloride (0.19 g). the resulting precipitates were collected by filtration recrystallized from a mixture of acetone and diethyl ether