2-(4-chlorophenoxy)butanoyl chloride

反応条件: temp:0.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 5.8 G of 2-(4-chlorophenoxy)butyryl chloride (0.025 mol) are added dropwise, with stirring and whilst cooling with an ice bath at 0°C and working under nitrogen, to 3.65 g (0.025 mol) of indane-1,3-dione in 20 ml of pyridine containing two drops of piperidine. After stirring the mixture for 18 hours, it is poured onto ice and acidified with hydrochloric acid, and the resulting mixture is ectracted with chloroform. After evaporating the solvent, the residue is crystallised from ethyl acetate to give 1.55 g of pure 2-[2'-(4"-chlorophenoxy)butyryl]indane-1,3-dione, melting point 132°C. Empirical formula: C19H15O4Cl; molecular Weight: 342.79; Elementary analysis: After stirring the mixture for 18 hours it is poured onto ice After evaporating the solvent the residue is crystallised from ethyl acetate

反応条件: temp:0.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 5.8 G of 2-(4-chlorophenoxy)butyryl chloride (0.025 mol) are added dropwise, with stirring and whilst cooling with an ice bath at 0°C and working under nitrogen, to 3.65 g (0.025 mol) of indane-1,3-dione in 20 ml of pyridine containing two drops of piperidine. After stirring the mixture for 18 hours, it is poured onto ice and acidified with hydrochloric acid, and the resulting mixture is ectracted with chloroform. After evaporating the solvent, the residue is crystallised from ethyl acetate to give 1.55 g of pure 2-[2'-(4"-chlorophenoxy)butyryl]indane-1,3-dione, melting point 132°C. Empirical formula: C19H15O4Cl; molecular Weight: 342.79; Elementary analysis: After stirring the mixture for 18 hours it is poured onto ice After evaporating the solvent the residue is crystallised from ethyl acetate

反応条件: temp:0.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 5.8 G of 2-(4-chlorophenoxy)butyryl chloride (0.025 mol) are added dropwise, with stirring and whilst cooling with an ice bath at 0°C and working under nitrogen, to 3.65 g (0.025 mol) of indane-1,3-dione in 20 ml of pyridine containing two drops of piperidine. After stirring the mixture for 18 hours, it is poured onto ice and acidified with hydrochloric acid, and the resulting mixture is ectracted with chloroform. After evaporating the solvent, the residue is crystallised from ethyl acetate to give 1.55 g of pure 2-[2'-(4"-chlorophenoxy)butyryl]indane-1,3-dione, melting point 132°C. Empirical formula: C19H15O4Cl; molecular Weight: 342.79; Elementary analysis: After stirring the mixture for 18 hours it is poured onto ice After evaporating the solvent the residue is crystallised from ethyl acetate