oxonan-2-one

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:80.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 43.5 g (345 mmol) of cyclooctanone (compound of formula (VI) with n=6) (ACROS) are placed in solution in 430 ml of dichloroethane. 170 g (985 mmol) of meta-chloroperbenzoic acid are then added. The medium is heated to 80° C. for 48 hours. At room temperature, 400 ml of a Na2S2O5 and NaHCO3 saturated solution (1/1 v/v) are added. The medium is strongly stirred for 18 hours. The organic phase is separated and placed into the presence of KI and H2O for 6 hours. The organic phase is separated and washed with a Na2S2O3 saturated solution, with a NaCl saturated solution, and is then dried on MgSO4, filtered and concentrated in vacuo in order to obtain 36 g of crude product. The organic phase is separated placed into the presence of KI and H2O for 6 hours The organic phase is separated washed with a Na2S2O3 saturated solution, with a NaCl saturated solution is then dried on MgSO4 filtered concentrated in vacuo in order

反応条件: temp:80.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 43.5 g (345 mmol) of cyclo-octanone is placed in solution in 430 ml of dichloroethane. 170 g (985 mmol) of meta-chloroperbenzoic acid is then added. The medium is heated to 80° C. for 48 hours. At room temperature, 400 ml of a Na2S2O5 and NaHCO3 saturated solution (1/1 v/v) are added. The medium is stirred vigorously for 18 hours. The organic phase is separated and contacted with Kl and H2O for 6 hours. The organic phase is separated and washed with a saturated solution of Na2S2O3, a saturated solution of NaCl then dried on MgSO4, filtered and concentrated under vacuum to give 36 g of the crude product. The organic phase is separated contacted with Kl and H2O for 6 hours The organic phase is separated washed with a saturated solution of Na2S2O3 a saturated solution of NaCl then dried on MgSO4 filtered concentrated under vacuum