diethyl 2,3-dioxobutanedioate

反応条件: temp:70.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (50.0 g), acetic acid (900 ml), 1,3-dibromo-5,5-dimethylhydantoin (149.1 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (750 mg) were mixed, and the reaction solution was stirred at 70° C. for 2 hours, followed by stirring at room temperature for 16 hours. The reaction solution was concentrated under reduced pressure until its volume became approximately 300 ml to obtain a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. by stirring at room temperature for 16 hours The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:70.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (50.0 g), acetic acid (900 ml), 1,3-dibromo-5,5-dimethylhydantoin (149.1 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (750 mg) were mixed, and the reaction solution was stirred at 70° C. for 2 hours, followed by stirring at room temperature for 16 hours. The reaction solution was concentrated under reduced pressure until its volume became approximately 300 ml to obtain a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. by stirring at room temperature for 16 hours The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (2.0 g), acetic acid (20 ml), 1,3-dibromo-5,5-dimethylhydantoin (6.0 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (30 mg) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 10 ml to afford a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (10.0 g), acetic acid (100 ml), N-bromosuccinimide (34.5 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (0.15 g) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 50 ml to afford a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (10.0 g), acetic acid (100 ml), N-bromosuccinimide (34.5 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (0.15 g) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 50 ml to afford a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (100.3 g), acetic acid (1 l), 1,3-dibromo-5,5-dimethylhydantoin (304 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (1.5 g) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 500 ml to afford a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (300 g), acetic acid (3 l), 1,3-dibromo-5,5-dimethylhydantoin (894 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (4.5 g) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 1.5 l to afford a solution of the title compound in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:70.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (50.0 g), acetic acid (900 ml), 1,3-dibromo-5,5-dimethylhydantoin (149.1 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (750 mg) were mixed, and the reaction solution was stirred at 70° C. for 2 hours, followed by stirring at room temperature for 16 hours. The reaction solution was concentrated under reduced pressure until its volume became approximately 300 ml to obtain a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. by stirring at room temperature for 16 hours The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (2.0 g), acetic acid (20 ml), 1,3-dibromo-5,5-dimethylhydantoin (6.0 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (30 mg) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 10 ml to afford a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (10.0 g), acetic acid (100 ml), N-bromosuccinimide (34.5 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (0.15 g) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 50 ml to afford a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (100.3 g), acetic acid (1 l), 1,3-dibromo-5,5-dimethylhydantoin (304 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (1.5 g) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 500 ml to afford a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume

反応条件: temp:55.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: L-Tartaric acid diethyl ester (300 g), acetic acid (3 l), 1,3-dibromo-5,5-dimethylhydantoin (894 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (4.5 g) were mixed, and the reaction solution was stirred at 55° C. for 3 hours. The reaction solution was concentrated under reduced pressure until its volume became 1.5 l to afford a solution of the title compound in acetic acid as a yellow liquid. The reaction solution was concentrated under reduced pressure until its volume