2,6-dibromobenzoyl chloride

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 2-(3,4,5-Trichlorophenyl)-1,2,4-oxadiazolidin-3,5-dione (0.03 mole), toluene (100 ml) and triethylamine (5 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2,6-Dibromobenzoyl chloride (0.03 mole) dissolved in toluene (20 ml) is then added to the reaction flask and the resulting mixture is heated at reflux with stirring for a period of about 24 hours. After this time the reaction mixture is filtered and the filtrate is washed with water, dilute hydrochloric acid and with aqueous sodium bicarbonate. The washed solution is then dried over anhydrous magnesium sulfate. The dried solution is stripped of solvent under reduced pressure leaving a solid residue. The residue is recrystallized to yield the desired product 2-(3,4,5-trichlorophenyl)-4-(2,6-dibromobenzoyl)-1,2,4-oxadiazolidin-3,5-dione. equipped with a mechanical stirrer thermometer and reflux condenser is then added to the reaction flask the resulting mixture is heated at reflux After this time the reaction mixture is filtered the filtrate is washed with water, dilute hydrochloric acid and with aqueous sodium bicarbonate The washed solution is then dried over anhydrous magnesium sulfate leaving a solid residue The residue is recrystallized

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 2-(3,4,5-Trichlorophenyl)-1,2,4-oxadiazolidin-3,5-dione (0.03 mole), toluene (100 ml) and triethylamine (5 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2,6-Dibromobenzoyl chloride (0.03 mole) dissolved in toluene (20 ml) is then added to the reaction flask and the resulting mixture is heated at reflux with stirring for a period of about 24 hours. After this time the reaction mixture is filtered and the filtrate is washed with water, dilute hydrochloric acid and with aqueous sodium bicarbonate. The washed solution is then dried over anhydrous magnesium sulfate. The dried solution is stripped of solvent under reduced pressure leaving a solid residue. The residue is recrystallized to yield the desired product 2-(3,4,5-trichlorophenyl)-4-(2,6-dibromobenzoyl)-1,2,4-oxadiazolidin-3,5-dione. equipped with a mechanical stirrer thermometer and reflux condenser is then added to the reaction flask the resulting mixture is heated at reflux After this time the reaction mixture is filtered the filtrate is washed with water, dilute hydrochloric acid and with aqueous sodium bicarbonate The washed solution is then dried over anhydrous magnesium sulfate leaving a solid residue The residue is recrystallized