4-chloro-7-methoxy-1H-indole-2,3-dione

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 25.0 g (0.118 mole) of 4-chloro-7-methoxyisatin is taken up in 500 ml CH3OH at 60° and treated portionwise with 23.8 g of 97% p-toluenesulfonylhydrazine (≅ 23.1 g or 1.05 equivalents). The mixture is kept at ~60° for 15 minutes and then stirred at room temperature for 20 hours.

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 25.0 g (0.118 mole) of 4-chloro-7-methoxyisatin is taken up in 500 ml CH3OH at 60° and treated portionwise with 23.8 g of 97% p-toluenesulfonylhydrazine (≅ 23.1 g or 1.05 equivalents). The mixture is kept at ~60° for 15 minutes and then stirred at room temperature for 20 hours.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 25.0 g (0.118 mole) of 4-chloro-7-methoxyisatin is taken up in 500 ml of CH3OH at 60° and treated portionwise with 23.8 g of 97% p-toluenesulfonylhydrazine (≃23.1 g or 1.05 equivalents). The mixture is kept at ~60° for 15 minutes and then stirred at room temperature for 20 hours.

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 25.0 g (0.118 mole) of 4-chloro-7-methoxyisatin is taken up in 500 ml CH3OH at 60° and treated portionwise with 23.8 g of 97% p-toluenesulfonylhydrazine (≅ 23.1 g or 1.05 equivalents). The mixture is kept at ~60° for 15 minutes and then stirred at room temperature for 20 hours.