2-(aminomethyl)phenol;hydrochloride

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To a mixture of 6-bromo-4-methoxymethylene-4H-isoquinoline-1,3-dione (194 mg, 0.69 mmol) and 2-aminomethyl-phenol hydrochloride salt (110 mg, 0.69 mmol) in N,N-dimethylformamide (DMF) (5 mL) is added Et3N (0.145 mL, 1.04 mmol). The precipitate is filtered to give 76 mg (30%) of the title compound as a beige solid. MS (ESI) m/z 371.0 (M−H)−1. The precipitate is filtered