2-(2,6-dimethylphenyl)sulfanylethanol

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 18.2 g of 2-(2,6-dimethyl phenylthio) 1-hydroxy ethane and 50 ml chloroform are added in a flask and when the mixture is perfectly clear, it is cooled to 0°. To the solution 14.3 g of phosphorous tribromide are added while keeping the temperature to about 0°. After completion of the addition, the inner temperature is let to revert at ambiant temperature then heated to reflux for one hour. it is cooled to 0° to about 0° After completion of the addition then heated to reflux for one hour

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 35 g. 2,6-dimethyl thiophenol are dissolved in a solution of 15.6 g sodium hydroxide in 210 ml water, under stirring and inert atmospher. After complete dissolution 34 g chloro ethanol are added portionwise thereto and the milky suspension is thereafter heated to reflux for one hour. The mixture reverts to room temperature and is extracted three times with ester to isolate the thus formed oily product. The ethereous solutions are washed with water, dried on sodium sulphate, filtered and evaporated off. 2-(2,6-dimethyl phenylthio) 1-hydroxy ethane is obtained with a yield of 95%. It is further used for the next step without any purification are added portionwise the milky suspension is thereafter heated to reflux for one hour reverts to room temperature is extracted three times with ester to isolate the thus formed oily product The ethereous solutions are washed with water dried on sodium sulphate filtered evaporated off