octane-1-sulfonamide

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 1-(n-octylsulfonylamino)-8-aminoanthraquinone was prepared as follows. 1-amino-8-chloroanthraquinone (1.0g), n-octanesulfonamide (1.0g), potassium carbonate (1.0g), cupric acetate monohydrate (0.85g) and chlorobenzene (16.0g) were refluxed for 5.5 hours. The cooled mixture was filtered and aqueous methanol was added to the filtrate. The supernatant liquid was decanted and the remaining oil was dissolved in dichloromethane. On addition of methanol and partial evaporation of the solvent, the product separated as a red solid. The cooled mixture was filtered aqueous methanol was added to the filtrate The supernatant liquid was decanted the remaining oil was dissolved in dichloromethane On addition of methanol and partial evaporation of the solvent the product separated as a red solid

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 1,5-dichloroanthraquinone (1.0g), n-octanesulfonamide (0.77g), potassium carbonate (1.0g), cupric acetate monohydrate (1.0g) and chlorobenzene (15ml) were refluxed for 4 hours. The solvent was evaporated at reduced pressure and the residue was extracted with toluene. After filtration the extract was separated by chromatography on silica using toluene as eluent to give the desired product as the second fraction. The solvent was evaporated at reduced pressure the residue was extracted with toluene After filtration the extract was separated by chromatography on silica

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 1,5-dichloroanthraquinone (1.0g), n-octanesulfonamide (0.77g), potassium carbonate (1.0g), cupric acetate monohydrate (1.0g) and chlorobenzene (15ml) were refluxed for 4 hours. The solvent was evaporated at reduced pressure and the residue was extracted with toluene. After filtration the extract was separated by chromatography on silica using toluene as eluent to give the desired product as the second fraction. The solvent was evaporated at reduced pressure the residue was extracted with toluene After filtration the extract was separated by chromatography on silica

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A 100ml round bottom flask, equipped with a magnetic stirrer and cooling condenser, was charged with 1-chloroanthraquinone (2.0g), n-octylsulfonamide (3.0g), copper acetate (0.8g), potassium carbonate (0.8g) and o-dichlorobenzene (25ml). This mixture was slowly heated to reflux. After 2.5 hours the reaction mixture was cooled and filtered. Methanol was then added to induce precipitation, and after filtration the solid was recrystallized from a mixture of dichloromethane and methanol to give a yellow product. A 100ml round bottom flask, equipped with a magnetic stirrer cooling condenser This mixture was slowly heated to reflux After 2.5 hours the reaction mixture was cooled filtered Methanol was then added precipitation after filtration the solid was recrystallized from a mixture of dichloromethane and methanol to give a yellow product

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A 100ml round bottom flask, equipped with a magnetic stirrer and cooling condenser, was charged with 1-chloroanthraquinone (2.0g), n-octylsulfonamide (3.0g), copper acetate (0.8g), potassium carbonate (0.8g) and o-dichlorobenzene (25ml). This mixture was slowly heated to reflux. After 2.5 hours the reaction mixture was cooled and filtered. Methanol was then added to induce precipitation, and after filtration the solid was recrystallized from a mixture of dichloromethane and methanol to give a yellow product. A 100ml round bottom flask, equipped with a magnetic stirrer cooling condenser This mixture was slowly heated to reflux After 2.5 hours the reaction mixture was cooled filtered Methanol was then added precipitation after filtration the solid was recrystallized from a mixture of dichloromethane and methanol to give a yellow product

反応条件: temp:0.00; pressure:0.00; stir:

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 1-(n-octylsulfonylamino)-8-aminoanthraquinone was prepared as follows. 1-amino-8-chloroanthraquinone (1.0g), n-octanesulfonamide (1.0g), potassium carbonate (1.0g), cupric acetate monohydrate (0.85g) and chlorobenzene (16.0g) were refluxed for 5.5 hours. The cooled mixture was filtered and aqueous methanol was added to the filtrate. The supernatant liquid was decanted and the remaining oil was dissolved in dichloromethane. On addition of methanol and partial evaporation of the solvent, the product separated as a red solid. The cooled mixture was filtered aqueous methanol was added to the filtrate The supernatant liquid was decanted the remaining oil was dissolved in dichloromethane On addition of methanol and partial evaporation of the solvent the product separated as a red solid

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 1,5-dichloroanthraquinone (1.0g), n-octanesulfonamide (0.77g), potassium carbonate (1.0g), cupric acetate monohydrate (1.0g) and chlorobenzene (15ml) were refluxed for 4 hours. The solvent was evaporated at reduced pressure and the residue was extracted with toluene. After filtration the extract was separated by chromatography on silica using toluene as eluent to give the desired product as the second fraction. The solvent was evaporated at reduced pressure the residue was extracted with toluene After filtration the extract was separated by chromatography on silica

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A 100ml round bottom flask, equipped with a magnetic stirrer and cooling condenser, was charged with 1-chloroanthraquinone (2.0g), n-octylsulfonamide (3.0g), copper acetate (0.8g), potassium carbonate (0.8g) and o-dichlorobenzene (25ml). This mixture was slowly heated to reflux. After 2.5 hours the reaction mixture was cooled and filtered. Methanol was then added to induce precipitation, and after filtration the solid was recrystallized from a mixture of dichloromethane and methanol to give a yellow product. A 100ml round bottom flask, equipped with a magnetic stirrer cooling condenser This mixture was slowly heated to reflux After 2.5 hours the reaction mixture was cooled filtered Methanol was then added precipitation after filtration the solid was recrystallized from a mixture of dichloromethane and methanol to give a yellow product