6579-55-1

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Tosyl chloride (11.60 g, 60.80 mmol) was added in small portions to a stirred solution of 1-(2-Hydroxy-ethylamino)-propan-2-ol (3.60 g, 30.25 mmol) in anhydrous pyridine at 0° C. The reaction was stirred at room temperature for 24 h and then poured onto ice-water (200 ml). The mixture was extracted into DCM (100 ml). The organic extract washed with 2N HCl, water, and was evaporated in vaccuo to give a brown residue which was used without further purification. poured onto ice-water (200 ml) The mixture was extracted into DCM (100 ml) The organic extract washed with 2N HCl, water was evaporated in vaccuo to give a brown residue which was used without further purification

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Tosyl chloride (11.60 g, 60.80 mmol) was added in small portions to a stirred solution of 1-(2-Hydroxy-ethylamino)-propan-2-ol (3.60 g, 30.25 mmol) in anhydrous pyridine at 0° C. The reaction was stirred at room temperature for 24 h and then poured onto ice-water (200 ml). The mixture was extracted into DCM (100 ml). The organic extract washed with 2N HCl, water, and was evaporated in vaccuo to give a brown residue which was used without further purification. poured onto ice-water (200 ml) The mixture was extracted into DCM (100 ml) The organic extract washed with 2N HCl, water was evaporated in vaccuo to give a brown residue which was used without further purification

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Tosyl chloride (11.60 g, 60.80 mmol) was added in small portions to a stirred solution of 1-(2-Hydroxy-ethylamino)-propan-2-ol (3.60 g, 30.25 mmol) in anhydrous pyridine at 0° C. The reaction was stirred at room temperature for 24 h and then poured onto ice-water (200 ml). The mixture was extracted into DCM (100 ml). The organic extract was washed with 2N HCl, water, and was evaporated in vaccuo to give a brown residue which was used without further purification. poured onto ice-water (200 ml) The mixture was extracted into DCM (100 ml) The organic extract was washed with 2N HCl, water was evaporated in vaccuo to give a brown residue which was used without further purification