2,2-dimethoxyethoxybenzene

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A mixture of 31.3 g of phenol, 60.0 g of bromoacetaldehyde dimethyl acetal and 80 g of potassium carbonate was heated at 150° C. in 300 ml of dimethylformamide. After 4.5 hours the reaction mixture was cooled, added to water, and extracted with diethyl ether. Separation, drying and evaporation of the organic phase gave the crude product. Vacuum distillation, bp 88°-98° C./1 mm yielded the title compound as a colourless oil. After 4.5 hours the reaction mixture was cooled extracted with diethyl ether Separation drying evaporation of the organic phase gave the crude product Vacuum distillation, bp 88°-98° C./1 mm

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To 36 g of phenoxyacetaldehyde dimethyl acetal was added, dropwise, 40 ml of acetyl chloride and 0.5 ml of thionyl chloride. After 15 h at room temperature the solution was evaporated and the residue distilled under vacuum, 110°-120° C./1 mm, to yield the title compound as a colourless oil. After 15 h at room temperature the solution was evaporated the residue distilled under vacuum, 110°-120° C./1 mm