2,6-dimethyl-3-phenylmethoxyaniline

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Zinc dust is added in portions to a solution of 4-benzyloxy-2-nitro-m-xylene (83.8 g) in glacial acetic acid (715 ml). Addition is complete when the exothermic reaction subsides. The reaction mixture is filtered through Celite and the pad washed with acetic acid. The filtrate is concentrated in vacuo and the residue diluted with H2O and made basic with ammonium hydroxide, and extracted with chloroform. The combined organic extracts are dried and concentrated in vacuo to give the desired aniline in quantitative crude yield. Addition the exothermic reaction subsides The reaction mixture is filtered through Celite the pad washed with acetic acid The filtrate is concentrated in vacuo the residue diluted with H2O extracted with chloroform The combined organic extracts are dried concentrated in vacuo

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Zinc dust is added in portions to a solution of 4-benzyloxy-2-nitro-m-xylene (83.8 g) in glacial acetic acid (715 ml). Addition is complete when the exothermic reaction subsides. The reaction mixture is filtered through Celite and the pad washed with acetic acid. The filtrate is concentrated in vacuo and the residue diluted with H2O and made basic with ammonium hydroxide, and extracted with chloroform. The combined organic extracts are dried and concentrated in vacuo to give the desired aniline in quantitative crude yield. Addition the exothermic reaction subsides The reaction mixture is filtered through Celite the pad washed with acetic acid The filtrate is concentrated in vacuo the residue diluted with H2O extracted with chloroform The combined organic extracts are dried concentrated in vacuo

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Zinc dust is added in portions to a solution of 4-benzyloxy-2-nitro-m-xylene (83.8 g) in glacial acetic acid (715 ml). Addition is complete when the exothermic reaction subsides. The reaction mixture is filtered through Celite and the pad washed with acetic acid. The filtrate is concentrated in vacuo and the residue diluted with H2O and made basic with ammonium hydroxide, and extracted with chloroform. The combined organic extracts are dried and concentrated in vacuo to give the desired aniline in quantitative crude yield. Addition the exothermic reaction subsides The reaction mixture is filtered through Celite the pad washed with acetic acid The filtrate is concentrated in vacuo the residue diluted with H2O extracted with chloroform The combined organic extracts are dried concentrated in vacuo

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Zinc dust is added in portions to a solution of 4 benzyloxy-2-nitro-m-xylene (83.8 g) in glacial acetic acid (715 ml) Addition is complete when the exothermic reaction subsides. The reaction mixture is filtered through celite and the pad washed with acetic acid. The filtrate is concentrated in vacuo and the residue diluted with H2O and made basic with ammonium hydroxide, and extracted with chloroform. The combined organic extracts are dried and concentrated in vacuo to give the desired aniline in quantitative crude yield. the exothermic reaction subsides The reaction mixture is filtered through celite the pad washed with acetic acid The filtrate is concentrated in vacuo the residue diluted with H2O extracted with chloroform The combined organic extracts are dried concentrated in vacuo

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Zinc dust is added in portions to a solution of 4-benzyloxy-2-nitro-m-xylene (83.8 g) in glacial acetic acid (715 ml). Addition is complete when the exothermic reaction subsides. The reaction mixture is filtered through Celite and the pad washed with acetic acid. The filtrate is concentrated in vacuo and the residue diluted with H2O and made basic with ammonium hydroxide, and extracted with chloroform. The combined organic extracts are dried and concentrated in vacuo to give the desired aniline in quantitative crude yield. Addition the exothermic reaction subsides The reaction mixture is filtered through Celite the pad washed with acetic acid The filtrate is concentrated in vacuo the residue diluted with H2O extracted with chloroform The combined organic extracts are dried concentrated in vacuo

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: Zinc dust is added in portions to a solution of 4-benzyloxy-2-nitro-m-xylene (83.8 g) in glacial acetic acid (715 ml). Addition is complete when the exothermic reaction subsides. The reaction mixture is filtered through Celite and the pad washed with acetic acid. The filtrate is concentrated in vacuo and the residue diluted with H2O and made basic with ammonium hydroxide, and extracted with chloroform. The combined organic extracts are dried and concentrated in vacuo to give the desired aniline in quantitative crude yield. Addition the exothermic reaction subsides The reaction mixture is filtered through Celite the pad washed with acetic acid The filtrate is concentrated in vacuo the residue diluted with H2O extracted with chloroform The combined organic extracts are dried concentrated in vacuo