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O(C(C)C)C1C=CC=C(C=O)C=1製品情報
3-ISOPROPOXY-BENZALDEHYDE (CAS 75792-33-5) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
想定用途
専門的研究・工業用途限定
データベース ID 712914
安全上の注意
For professional research and industrial use only. Review the supplier safety data sheet before handling.
合成データ
12 反応 · 12 文献
反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-7a2ce767b6fe405e962459d559afe442反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-4cdd5ad203894fc18e41f189eaf34c58反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-9d6ec31641c74f7ca3bffe0b57630092反応条件: temp:0.00; pressure:0.00; stir:
ソース ID: ord-7a2ce767b6fe405e962459d559afe442反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: 3-Isopropoxybenzaldehyde was prepared from 3-hydroxybenzaldehyde and isopropyl iodide analogous to the procedure described in Example 361. By using the procedure of Example 151 this aldehyde was transformed to 2-(3-isopropoxyphenyl)ethylamine, which was reacted with the product of Example 103, following the procedure of Example 105 to give the titled product.
ソース ID: ord-e159b6f5e8b74ad6a5b27b503254cc59反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: EX-645A) 3-Hydroxybenzaldehyde (5.60 g, 45.9 mmol) and 2-iodopropane (7.86 g, 46.2 mmol) were dissolved in 50 mL of isopropanol. Potassium carbonate (20 g, 145 mmol) was added, and the mixture was heated to reflux for 8 h, at which time TLC analysis indicated that the reaction had gone to completion. Water was added to dissolve all solids, and the mixture was extracted with ether (3×). The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×), and finally with brine. The solution was dried over MgSO4, filtered, and evaporated to give 5.03 g (67%) of the desired 3-isopropoxybenzaldehyde product as a pale oil. 1H NMR (C6D6) δ9.62 (s, 1H), 7.29 (s, 1H), 7.03 (m, 1H), 6.91 (t, 1H), 6.84 (m, 1H), 4.03 (septet, 1H), 0.96 (d, 6H). the mixture was heated to reflux for 8 h, at which time TLC analysis to dissolve all solids the mixture was extracted with ether (3×) The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×) The solution was dried over MgSO4 filtered evaporated
ソース ID: ord-51802622670e448c9bc229fc8f67d970反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: EX-645A) 3-Hydroxybenzaldehyde (5.60 g, 45.9 mmol) and 2-iodopropane (7.86 g, 46.2 mmol) were dissolved in 50 mL of isopropanol. Potassium carbonate (20 g, 145 mmol) was added, and the mixture was heated to reflux for 8 h, at which time TLC analysis indicated that the reaction had gone to completion. Water was added to dissolve all solids, and the mixture was extracted with ether (3×). The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×), and finally with brine. The solution was dried over MgSO4, filtered, and evaporated to give 5.03 g (67%) of the desired 3-isopropoxybenzaldehyde product as a pale oil. 1H NMR (C6D6) δ9.62 (s, 1H), 7.29 (s, 1H), 7.03 (m, 1H), 6.91 (t, 1H), 6.84 (m, 1H), 4.03 (septet, 1H), 0.96 (d, 6H). the mixture was heated to reflux for 8 h, at which time TLC analysis to dissolve all solids the mixture was extracted with ether (3×) The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×) The solution was dried over MgSO4 filtered evaporated
ソース ID: ord-51802622670e448c9bc229fc8f67d970反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: EX-645A) 3-Hydroxybenzaldehyde (5.60 g, 45.9 mmol) and 2-iodopropane (7.86 g, 46.2 mmol) were dissolved in 50 mL of isopropanol. Potassium carbonate (20 g, 145 mmol) was added, and the mixture was heated to reflux for 8 h, at which time TLC analysis indicated that the reaction had gone to completion. Water was added to dissolve all solids, and the mixture was extracted with ether (3×). The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×), and finally with brine. The solution was dried over MgSO4, filtered, and evaporated to give 5.03 g (67%) of the desired 3-isopropoxybenzaldehyde product as a pale oil. 1H NMR (C6D6) δ9.62 (s, 1H), 7.29 (s, 1H), 7.03 (m, 1H), 6.91 (t, 1H), 6.84 (m, 1H), 4.03 (septet, 1H), 0.96 (d, 6H). the mixture was heated to reflux for 8 h, at which time TLC analysis to dissolve all solids the mixture was extracted with ether (3×) The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×) The solution was dried over MgSO4 filtered evaporated
ソース ID: ord-cc108b6746dd478eb293b7b0db990264反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: EX-645A) 3-Hydroxybenzaldehyde (5.60 g, 45.9 mmol) and 2-iodopropane (7.86 g, 46.2 mmol) were dissolved in 50 mL of isopropanol. Potassium carbonate (20 g, 145 mmol) was added. and the mixture was heated to reflux for 8 h, at which time TLC analysis indicated that the reaction had gone to completion. Water was added to dissolve all solids, and the mixture was extracted with ether (3×). The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×), and finally with brine. The solution was dried over MgSO4, filtered, and evaporated to give 5.03 g (67%) of the desired 3-isopropoxybenzaldehyde product as a pale oil. 1H NMR (C6D6) δ9.62 (s, 1H), 7.29 (s, 1H), 7.03 (m, 1H), 6.91 (t, 1H), 6.84 (m, 1H), 4.03 (septet, 1H), 0.96 (d, 6H). and the mixture was heated to reflux for 8 h, at which time TLC analysis to dissolve all solids the mixture was extracted with ether (3×) The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×) The solution was dried over MgSO4 filtered evaporated
ソース ID: ord-a0d8b28ca56144a1a4a84e0c24096275反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: EX-645A) 3-Hydroxybenzaldehyde (5.60 g, 45.9 mmol) and 2-iodopropane (7.86 g, 46.2 mmol) were dissolved in 50 mL of isopropanol. Potassium carbonate (20 g, 145 mmol) was added. and the mixture was heated to reflux for 8 h, at which time TLC analysis indicated that the reaction had gone to completion. Water was added to dissolve all solids, and the mixture was extracted with ether (3×). The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×), and finally with brine. The solution was dried over MgSO4, filtered, and evaporated to give 5.03 g (67%) of the desired 3-isopropoxybenzaldehyde product as a pale oil. 1H NMR (C6D6) δ9.62 (s, 1H), 7.29 (s, 1H), 7.03 (m, 1H), 6.91 (t, 1H), 6.84 (m, 1H), 4.03 (septet, 1H), 0.96 (d, 6H). and the mixture was heated to reflux for 8 h, at which time TLC analysis to dissolve all solids the mixture was extracted with ether (3×) The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4×) The solution was dried over MgSO4 filtered evaporated
ソース ID: ord-a0d8b28ca56144a1a4a84e0c24096275反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: EX-645A) 3-Hydroxybenzaldehyde (5.60 g, 45.9 mmol) and 2-iodopropane (7.86 g, 46.2 mmol) were dissolved in 50 mL of isopropanol. Potassium carbonate (20 g, 145 mmol) was added, and the mixture was heated to reflux for 8 h, at which time TLC analysis indicated that the reaction had gone to completion. Water was added to dissolve all solids, and the mixture was extracted with ether (3x). The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4x), and finally with brine. The solution was dried over MgSO4, filtered, and evaporated to give 5.03 g (67%) of the desired 3-isopropoxybenzaldehyde product as a pale oil. 1H NMR (C6D6) δ 9.62 (s, 1H), 7.29 (s, 1H), 7.03 (m, 1H), 6.91 (t, 1H), 6.84 (m, 1H), 4.03 (septet, 1H), 0.96 (d, 6H). the mixture was heated to reflux for 8 h, at which time TLC analysis to dissolve all solids the mixture was extracted with ether (3x) The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4x) The solution was dried over MgSO4 filtered evaporated
ソース ID: ord-0e5684627b3747428380152ea872789a反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
実験手順: EX-645A) 3-Hydroxybenzaldehyde (5.60 g, 45.9 mmol) and 2-iodopropane (7.86 g, 46.2 mmol) were dissolved in 50 mL of isopropanol. Potassium carbonate (20 g, 145 mmol) was added, and the mixture was heated to reflux for 8 h, at which time TLC analysis indicated that the reaction had gone to completion. Water was added to dissolve all solids, and the mixture was extracted with ether (3x). The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4x), and finally with brine. The solution was dried over MgSO4, filtered, and evaporated to give 5.03 g (67%) of the desired 3-isopropoxybenzaldehyde product as a pale oil. 1H NMR (C6D6) δ 9.62 (s, 1H), 7.29 (s, 1H), 7.03 (m, 1H), 6.91 (t, 1H), 6.84 (m, 1H), 4.03 (septet, 1H), 0.96 (d, 6H). the mixture was heated to reflux for 8 h, at which time TLC analysis to dissolve all solids the mixture was extracted with ether (3x) The combined ether layer was washed with water, 2 M NaOH, again with water until clear (4x) The solution was dried over MgSO4 filtered evaporated
ソース ID: ord-0e5684627b3747428380152ea872789aPubChem References
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