2-chloro-4-ethylsulfanyl-1-fluorobenzene

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To a solution of 2-chloro-4-ethanesulphanyl-1-fluorobenzene (2.40 g) in DCM (100 mL) was added 75% m-chloroperbenzoic acid (4.35 g) and the mixture stirred at ambient temperature for 16 h. The mixture was washed successively with saturated potassium carbonate (30 mL) and brine (30 mL) then dried (MgSO4), filtered and reduced in vacuo. The resultant residue was chromatographed on silica (eluting with 0-50% ethyl acetate in iso-hexane) and the slower running product isolated (1.26 g). The mixture was washed successively with saturated potassium carbonate (30 mL) and brine (30 mL) then dried (MgSO4) filtered The resultant residue was chromatographed on silica (eluting with 0-50% ethyl acetate in iso-hexane) isolated (1.26 g)

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To a solution of 2-chloro-4-ethanesulphanyl-1-fluorobenzene (2.40 g) in DCM (100 mL) was added 75% m-chloroperbenzoic acid (4.35 g) and the mixture stirred at ambient temperature for 16 h. The mixture was washed successively with saturated potassium carbonate (30 mL) and brine (30 mL) then dried (MgSO4), filtered and reduced in vacuo. The resultant residue was chromatographed on silica (eluting with 0-50% ethyl acetate in iso-hexane) and the slower running product isolated (1.26 g). The mixture was washed successively with saturated potassium carbonate (30 mL) and brine (30 mL) then dried (MgSO4) filtered The resultant residue was chromatographed on silica (eluting with 0-50% ethyl acetate in iso-hexane) isolated (1.26 g)

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: To a solution of 2-chloro-4-ethanesulphanyl-1-fluorobenzene (2.40 g) in DCM (100 mL) was added 75% m-chloroperbenzoic acid (4.35 g) and the mixture stirred at ambient temperature for 16 h. The mixture was washed successively with saturated potassium carbonate (30 mL) and brine (30 mL) then dried (MgSO4), filtered and reduced in vacuo. The resultant residue was chromatographed on silica (eluting with 0-50% ethyl acetate in iso-hexane) and the slower running product isolated (1.26 g). The mixture was washed successively with saturated potassium carbonate (30 mL) and brine (30 mL) then dried (MgSO4) filtered The resultant residue was chromatographed on silica (eluting with 0-50% ethyl acetate in iso-hexane) isolated (1.26 g)