4-amino-3-chlorobenzaldehyde

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: After 6-hydroxy-2H-benzofuran-3-one 1 g and 3-chloro-4-aminobenzaldehyde 1.24 g were dissolved in methanol 75 ml, concentrated hydrochloric acid 50 ml was added, and the mixture was refluxed for 1.5 hours. The solution was cooled to room temperature, and precipitated crystals were filtered and dried over phosphorous pentoxide at a temperature of 60° C. for five hours under reduced pressure to obtain the desired compound 1.75 g. the mixture was refluxed for 1.5 hours precipitated crystals were filtered dried over phosphorous pentoxide at a temperature of 60° C. for five hours under reduced pressure