4-(cyclopropylmethoxy)-3-fluoroaniline

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A suspension of 1-(cyclopropylmethoxy)-2-fluoro-4-nitrobenzene (18.3 g) and 5% palladium carbon (containing water (50%), 1.84 g) in methanol (289 mL) was stirred for 3 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (15.2 g). The reaction mixture was filtered the filtrate was concentrated under reduced pressure

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: A mixture of 1-(cyclopropylmethoxy)-2-fluoro-4-nitrobenzene (3.00 g), 10% palladium-carbon (containing water (50%), 3.00 g) and THF (30 mL) was stirred at room temperature for 1 hr under a hydrogen atmosphere. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure to give the title compound (2.57 g). The catalyst was removed by filtration the obtained filtrate was concentrated under reduced pressure