tert-butyl N-(2-amino-4-bromophenyl)carbamate

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from the reaction of tert-butyl 2-amino-4-bromophenylcarbamate (Example B1; 1 mmol) and tert-butyl 3-oxo-3-(pyrazin-2-yl)propanoate (Example C3; 1 mmol) according to the general procedure D. Obtained as a yellow solid (81%), MS (EI) 435 [(M+1)+].

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from the reaction of tert-butyl 2-amino-4-bromophenylcarbamate (Example B1; 1 mmol) and tert-butyl 3-oxo-3-(pyridazin-4-yl)propanoate (Example C1; 1 mmol) according to the general procedure D. Obtained as a yellow solid (89%), MS (EI) 435 [(M+1)+].

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from the tert-butyl 4-bromo-2-nitrophenylcarbamate (Example A1; 3 mmol) by reduction with zinc according to the general procedure B. Obtained as a yellow solid (58%), MS (EI) 287 [(M+1)+].

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from the tert-butyl 4-bromo-2-nitrophenylcarbamate (Example A1; 3 mmol) by reduction with zinc according to the general procedure B. Obtained as a yellow solid (58%), MS (EI) 287 [(M+1)+].

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from the reaction of tert-butyl 2-amino-4-bromophenylcarbamate (Example B1; 1 mmol) and tert-butyl 3-oxo-3-(pyrazin-2-yl)propanoate (Example C3; 1 mmol) according to the general procedure D. Obtained as a yellow solid (81%), MS (EI) 435 [(M+1)+].

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from the reaction of tert-butyl 2-amino-4-bromophenylcarbamate (Example B1; 1 mmol) and tert-butyl 3-oxo-3-(pyridazin-4-yl)propanoate (Example C1; 1 mmol) according to the general procedure D. Obtained as a yellow solid (89%), MS (EI) 435 [(M+1)+].

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: The title compound was prepared from the tert-butyl 4-bromo-2-nitrophenylcarbamate (Example A1; 3 mmol) by reduction with zinc according to the general procedure B. Obtained as a yellow solid (58%), MS (EI) 287 [(M+1)+].