3-propylcyclopentan-1-one

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 32 ml of 15% n-butyllithium solution in hexane are added dropwise to a suspension of 18.07 g of 4-n-octyloxy-4'-bromobiphenyl in a mixture of toluene/tetrahydrofuran at -15°. After 15 minutes, a clear solution is obtained and a mixture of 6.31 g of 3-n-propylcyclopentanone and 25 ml of toluene/tetrahydrofuran is added dropwise. After the mixture has reacted for a further 16 hours at room temperature and after conventional work-up and column chromatography, 4-(1-hydroxy-3-n-propylcyclopentyl)-4-n-octyloxybiphenyl is obtained. a clear solution is obtained is added dropwise After the mixture has reacted for a further 16 hours at room temperature

反応条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

実験手順: 32 ml of 15% n-butyllithium solution in hexane are added dropwise to a suspension of 18.07 g of 4-n-octyloxy-4'-bromobiphenyl in a mixture of toluene/tetrahydrofuran at -15°. After 15 minutes, a clear solution is obtained and a mixture of 6.31 g of 3-n-propylcyclopentanone and 25 ml of toluene/tetrahydrofuran is added dropwise. After the mixture has reacted for a further 16 hours at room temperature and after conventional work-up and column chromatography, 4-(1-hydroxy-3-n-propylcyclopentyl)-4-n-octyloxybiphenyl is obtained. a clear solution is obtained is added dropwise After the mixture has reacted for a further 16 hours at room temperature